Project 1: Development of a colorimetric dosimeter for the evaluation of exposure to volatile compounds
One of the major sources of pollution is the workplaces in which the pollutant varies depending on the industry. Exposure to hazardous substances in the workplace can cause short-term as well as long-term health problems like irritation of the eyes, headache, cancer, central nervous system damage, and occupational asthma. Sensors are practical and economical way to monitor hazardous vapours in workplaces. The aim of the project is designing a simple and effective sensor badge, which can be clipped in or near a breathing zone for the duration of the work and indicate the exposure of pollutants within the limits of regulatory references based on OSHA, EU-OSHA, NIOSH and/or ACGIH.
Project 2: Wearable sensors for wound monitoring
Chronic wounds are a health burden for individuals and have a significant impact on health care systems. Wound diagnosis and assessment are mostly based on laboratory testing and do not consider the dynamic nature of the wound. Successful wound monitoring devices can decrease doctor visits as well as the cost of the lab testing. The aim of the project is designing wearable sensors to monitor chronic wounds by using its enzyme activity.
Project 3: Development of a biosensor array to monitor athletes’ performances
Physiological concentrations of lactate, pyruvate, uric acid and testosterone provide information about muscle state, oxygen transport, nutritional and hydration status, therefore they are widely used as indicators to assess health and training status of athletes. To date conventional methods such as enzymatic assay, immunoassay and chromatography have been applied to measure the concentration levels of such molecules in blood. However, they are costly, time consuming, need sample pre-treatment, and require trained personnel. Sensors may represent an interesting alternative to classical analytical techniques due to their proprieties like: low cost, fast response and sensitivity. The aim of the project is the development of an electrochemical biosensor array to allow the detection of: lactate, pyruvate, uric acid and testosterone in sweat. This multiple detection device will be able to monitor athletes’ performances and physical conditions, providing a broader level of information regarding injury risk and overtraining.
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Project 4: Electrochemical biosensor for pathogenic bacteria and important biomarkers detection
The selectivity and specificity provided by the use of biological recognition elements in the development of sensing technologies has attracted much interest in areas such as diagnostic medicine, food industry, environmental monitoring, among others. The use of electrochemical transduction techniques has a number of advantages for the development of biosensors, such as low-cost, simplicity, low detection limits, selectivity and potential for miniaturization. These features make techniques based on electrochemical transduction very attractive for the analysis in complex samples.
The aim of this project is the development of an electrochemical biosensor based on the use of a new biological elements (such as: CRISPR/Cas system, Phages, DNA self-assembled structure, engineered proteins) as a detection platform for Bacteria, Virus and important disease biomarkers, to overcome the high cost and long processing times of traditional techniques
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